Earlier in the tournament, Karman had caused an upset by defeating the second seed Robin Anderson (USA) in the first round and Japanese Ena Shibahara, one-half of the French Open 2022 mixed double champions in the second round.
Zverev had surgery on torn ligaments in his right ankle this month after he was forced to retire from his French Open semi-final against Rafael Nadal.
Images from Day 2 of the 2023 US Open at Flushing Meadows in New York on Tuesday.
Aryna Sabalenka rose above geopolitical tumult to become the first player to claim a Grand Slam title as a neutral at the Australian Open.
World No 1 Serena Williams overcame a dreadful second set to beat Germany's Sabine Lisicki.
They got the better of Flavia Pennetta and Akiko Morigami in the semi-final of the WTA Indian Open.
The fifth-seeded Austrian, who saved two match points, will face Novak Djokovic on Saturday after the world number one's opponent Marin Cilic withdrew with food poisoning.
They were beaten by Shinobu Asagoe and Katarina Srebotnik in the doubles final of the Bausch and Lomb Championships in Florida.
Sania Mirza and Liezel Huber were made to work hard by Darija Jurak and Heather Watson before making the quarter-finals in the WTA Aegon International, in Eastbourne, on Tuesday.
The pair would now lock horns with the third seeded pair of Beygelzimer and Fedak for the title at the centre court on Sunday.
'I have so much to look forward to in 2021, including the Olympics'
Top seed Venus Williams beat Flavia Pennetta while the Russian accounted for Eleni Daniilidou of Greece in Saturday's semi-finals.
Sania Mirza and Bethanie Mattek-Sands will have to wait for their third title of the season as they ended runners-up at the WTA Porsche Tennis Grand Prix after losing the summit clash to Sabine Lisicki and Mona Barthel, in Stuttgart on Sunday.
Williams reached the final of the mixed team event earlier this year with American compatriot John Isner to kick off a superb season where she won the Australian and French Opens and Wimbledon to take her grand slam singles haul to 21.
Marion Bartoli will play Aravane Rezai in an all-French final at the Tournament of Champions in Bali after both claimed straight-sets victories on Saturday.
Denmark's Caroline Wozniacki battled back after a mid-match slump to beat Angelique Kerber of Germany on Friday and book a place in the semi-finals of the Pan Pacific Open.
World No 1 Victoria Azarenka of Belarus charged into the final of the Indian Wells WTA tournament with a 6-4, 6-3 victory over Germany's Angelique Kerber on Friday.
Maria Sharapova's return from injury after an almost three-month break was cut short on Monday after the world number three suffered an arm injury at the Wuhan Open in China.
Images from Day 3 of the US Open, at Flushing Meadows, New York.
The Indo-US pair got a walkover in the semi-finals, as their opponents, Camille Pin and Milagros Sequera, pulled out because of illness.
Top seed Caroline Wozniacki of Denmark and 15th-seeded Frenchwoman Marion Bartoli advanced smoothly to the final of the Indian Wells WTA tournament with commanding victories on Friday.
Sania Mirza and her Swiss partner Martina Hingis lost 2-6, 6-4, 10-5 to Russian pair Elena Vesnina and Daria Kasatkina late on Thursday night.
Russian and Belarusian players will be allowed to compete at the US Open this year but only as neutrals, the United States Tennis Association (USTA) announced on Tuesday.
The 24-year-old Tunisian is the only player from the continent in the women's draw and only the second Arabic woman ever to crack the top 100 in the WTA rankings.
Top seed Roger Federer will challenge for a ninth Halle Open title after reaching the Wimbledon warm-up event final with a 6-4 7-6(5) victory over rising Russian talent Karen Khachanov on Saturday.
The Indian ace registered an easy 6-2, 6-1 victory over Italy's Roberta Vinci at the Forest Hills Women's Tennis Classic.
Sabalenka overpowers Raducanu, Osaka falls
World number one Iga Swiatek defeated American Jessica Pegula 6-3, 6-0 in just over an hour to defend her Qatar Open title on Saturday.
Runner-up Pliskova will move into the top-10 of the world rankings for the first time in her career
Rafa Nadal returned from an injury layoff to beat Miomir Kecmanovic 6-1 7-6(4) on Wednesday
Multiple Grand Slam winner Martina Navratilova questioned the "silence" of the International Tennis Federation after one of its members described world number one Serena Williams and older sister Venus as "brothers".
Putting up yet another dominating performance, defending champions Sania Mirza and Cara Black outclassed Jelena Jankovic and Arantxa Parra Santonja 6-3, 6-2 to reach the summit clash of the WTA Toray Pan Pacific Open, in Tokyo on Friday.
Sania Mirza has received another lift in her already booming career. The Indian tennis ace reached the 25th doubles final of her career at the WTA New Haven Open.
Medvedev moved a step closer to a potential semi-final showdown with Novak Djokovic at the Australian Open warm-up event.
The third seeded Indian ace easily beat Olga Govortsova of Belarus at the US $175,000 WTA Tier III event.
Romania's Simona Halep overcame Czech Karolina Pliskova 6-4, 7-6(4) in the final of the Dubai Championships on Saturday to claim her 10th WTA singles title.
The Indian ace and her Chinese partner Yang-Jan Chan beat Mervana Jugic-Salkic of Bosnia and Italy's Romina Oprandi in the semi-finals.
Sania Mirza and Elena Vesnina recovered from a second-set lapse against Timea Bacsinszky and Alberta Brianti to advance to the doubles quarter-finals of the Indian Wells WTA Premier event.
The 26-year-old first reached the top last October but lost the spot 16 weeks later having not hoisted a Grand Slam trophy.